CAMK Ser/Thr protein kinase family

Family CAMK Ser/Thr protein kinase family (74 members)

28 members not classified in subfamilies

10 subfamilies

Subfamily AMPK subfamily (2 members)

2 members

SIK1 , SIK1B

Subfamily CaMK subfamily (13 members)

13 members

Subfamily CHK2 subfamily (1 member)

1 member

CHEK2

Subfamily DAP kinase subfamily (5 members)

5 members

Subfamily LKB1 subfamily (1 member)

1 member

STK11

Subfamily NIM1 subfamily (1 member)

1 member

CHEK1

Subfamily PIM subfamily (3 members)

3 members

PIM1 , PIM2 , PIM3

Subfamily PKD subfamily (3 members)

3 members

PRKD1 , PRKD2 , PRKD3

Subfamily SNF1 subfamily (14 members)

14 members

Subfamily Tribbles subfamily (3 members)

3 members

TRIB1 , TRIB2 , TRIB3

Family ADCK protein kinase family (5 members)

5 members

Family AGC Ser/Thr protein kinase family (58 members)

15 members not classified in subfamilies

8 subfamilies

Subfamily cAMP subfamily (5 members)

5 members

Subfamily cGMP subfamily (2 members)

2 members

PRKG1 , PRKG2

Subfamily DMPK subfamily (4 members)

4 members

CDC42BPA , CDC42BPB , CDC42BPG , DMPK

Subfamily GPRK subfamily (7 members)

7 members

Subfamily PDPK1 subfamily (2 members)

2 members

PDPK1 , PDPK2P

Subfamily PKC subfamily (12 members)

12 members

Subfamily RAC subfamily (3 members)

3 members

AKT1 , AKT2 , AKT3

Subfamily S6 kinase subfamily (8 members)

8 members

Family Alpha-type protein kinase family (4 members)

1 member not classified in subfamilies

EEF2K

1 subfamily

Subfamily ALPK subfamily (3 members)

3 members

ALPK1 , ALPK2 , ALPK3

Family BUD32 family (1 member)

1 member

TP53RK

Family CK1 Ser/Thr protein kinase family (12 members)

2 members not classified in subfamilies

TTBK1 , TTBK2

2 subfamilies

Subfamily Casein kinase I subfamily (7 members)

7 members

Subfamily VRK subfamily (3 members)

3 members

VRK1 , VRK2 , VRK3

Family CMGC Ser/Thr protein kinase family (62 members)

4 members not classified in subfamilies

PRPF4B , SRPK1 , SRPK2 , SRPK3

6 subfamilies

Subfamily CDC2/CDKX subfamily (29 members)

29 members

Subfamily GSK-3 subfamily (2 members)

2 members

GSK3A , GSK3B

Subfamily HIPK subfamily (4 members)

4 members

HIPK1 , HIPK2 , HIPK3 , HIPK4

Subfamily Lammer subfamily (4 members)

4 members

CLK1 , CLK2 , CLK3 , CLK4

Subfamily MAP kinase subfamily (14 members)

14 members

Subfamily MNB/DYRK subfamily (5 members)

5 members

Family NEK Ser/Thr protein kinase family (11 members)

1 subfamily

Subfamily NIMA subfamily (11 members)

11 members

Family PAN3 family (1 member)

1 member

PAN3

Family RIO-type Ser/Thr kinase family (3 members)

3 members

RIOK1 , RIOK2 , RIOK3

Family Ser/Thr protein kinase family (67 members)

27 members not classified in subfamilies

13 subfamilies

Subfamily APG1/unc-51/ULK1 subfamily (4 members)

4 members

ULK1 , ULK2 , ULK3 , ULK4

Subfamily Aurora subfamily (3 members)

3 members

AURKA , AURKB , AURKC

Subfamily BUB1 subfamily (2 members)

2 members

BUB1 , BUB1B

Subfamily CDC5/Polo subfamily (5 members)

5 members

Subfamily CDC7 subfamily (1 member)

1 member

CDC7

Subfamily CK2 subfamily (3 members)

3 members

CSNK2A1 , CSNK2A2 , CSNK2A3

Subfamily GCN2 subfamily (4 members)

4 members

EIF2AK1 , EIF2AK2 , EIF2AK3 , EIF2AK4

Subfamily Haspin subfamily (1 member)

1 member

HASPIN

Subfamily I-kappa-B kinase subfamily (4 members)

4 members

CHUK , IKBKB , IKBKE , TBK1

Subfamily S6 kinase subfamily (2 members)

2 members

RPS6KC1 , RPS6KL1

Subfamily STKL subfamily (4 members)

4 members

POMK , SBK2 , SBK3 , STKLD1

Subfamily WEE1 subfamily (3 members)

3 members

PKMYT1 , WEE1 , WEE2

Subfamily WNK subfamily (4 members)

4 members

WNK1 , WNK2 , WNK3 , WNK4

Family STE Ser/Thr protein kinase family (54 members)

3 subfamilies

Subfamily MAP kinase kinase kinase subfamily (17 members)

17 members

Subfamily MAP kinase kinase subfamily (8 members)

8 members

Subfamily STE20 subfamily (29 members)

29 members

Family TKL Ser/Thr protein kinase family (34 members)

13 members not classified in subfamilies

5 subfamilies

Subfamily MAP kinase kinase kinase subfamily (1 member)

1 member

TNNI3K

Subfamily Pelle subfamily (4 members)

4 members

IRAK1 , IRAK2 , IRAK3 , IRAK4

Subfamily RAF subfamily (3 members)

3 members

ARAF , BRAF , RAF1

Subfamily ROCO subfamily (1 member)

1 member

LRRK1

Subfamily TGFB receptor subfamily (12 members)

12 members

Family Tyr protein kinase family (90 members)

11 members not classified in subfamilies

17 subfamilies

Subfamily ABL subfamily (2 members)

2 members

ABL1 , ABL2

Subfamily AXL/UFO subfamily (3 members)

3 members

AXL , MERTK , TYRO3

Subfamily BRK/PTK6/SIK subfamily (1 member)

1 member

PTK6

Subfamily CSF-1/PDGF receptor subfamily (8 members)

8 members

Subfamily CSK subfamily (2 members)

2 members

CSK , MATK

Subfamily EGF receptor subfamily (4 members)

4 members

EGFR , ERBB2 , ERBB3 , ERBB4

Subfamily Ephrin receptor subfamily (14 members)

14 members

Subfamily FAK subfamily (2 members)

2 members

PTK2 , PTK2B

Subfamily Fes/fps subfamily (2 members)

2 members

FER , FES

Subfamily Fibroblast growth factor receptor subfamily (4 members)

4 members

FGFR1 , FGFR2 , FGFR3 , FGFR4

Subfamily Insulin receptor subfamily (12 members)

12 members

Subfamily JAK subfamily (4 members)

4 members

JAK1 , JAK2 , JAK3 , TYK2

Subfamily ROR subfamily (2 members)

2 members

ROR1 , ROR2

Subfamily SRC subfamily (10 members)

10 members

Subfamily SYK/ZAP-70 subfamily (2 members)

2 members

SYK , ZAP70

Subfamily TEC subfamily (5 members)

5 members

Subfamily Tie subfamily (2 members)

2 members

TEK , TIE1

Members	Human proteins	All
Members	74	454
Drug targets	0	0
With known 3D structures	43	76
With tested compounds	52	63
With active compounds (<100nM)	49	52
With mutations reported	71	71

CAMK Ser/Thr protein kinase family

Lineage