2G0H logo

2G0H

3D Structure View

Loading...

More Info

GENERAL
TITLE
STRUCTURE-BASED DRUG DESIGN OF A NOVEL FAMILY OF PPAR PARTIAL AGONISTS: VIRTUAL SCREENING, X-RAY CRYSTALLOGRAPHY AND IN VITRO/IN VIVO BIOLOGICAL ACTIVITIES
DATE LAST MODIFIED
24 Feb 2009
RELEASE
16 May 2006
OBSOLETE
CLASSIFICATION
TRANSCRIPTION ACTIVATOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
20
PUBMED ID
DOI
10.1021/JM051129S
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P37231 PPARG, NR1C3 ESCHERICHIA COLI BL21(DE3) HUMAN
PPAR-GAMMA
Mutations
P37231 PPARG, NR1C3 ESCHERICHIA COLI BL21(DE3) HUMAN
PPAR-GAMMA
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402