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GENERAL
TITLE
DISCOVERY OF POTENT, ORALLY ACTIVE, NONPEPTIDE INHIBITORS OF HUMAN MAST CELL CHYMASE BY USING STRUCTURE-BASED DRUG DESIGN
DATE LAST MODIFIED
20 Oct 2021
RELEASE
12 Jun 2007
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43
RESOLUTION RANGE HIGH
2.6
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1021/JM0700619
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P23946 -- SPODOPTERA FRUGIPERDA HUMAN
MAST CELL PROTEASE I
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402