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GENERAL
TITLE
CRYSTAL STRUCTURE OF AN AUTOIMMUNE COMPLEX BETWEEN A HUMAN IGM RHEUMATOID FACTOR AND IGG1 FC REVEALS A NOVEL FC EPITOPE AND EVIDENCE FOR AFFINITY MATURATION
DATE LAST MODIFIED
11 May 2022
RELEASE
10 Apr 2007
OBSOLETE
CLASSIFICATION
IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
3
RESOLUTION RANGE LOW
25
PUBMED ID
DOI
10.1016/J.JMB.2007.02.085

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P01857 -- CRICETULUS GRISEUS HUMAN IGG1 HUMAN
IGG1
Mutations
P01857 -- CRICETULUS GRISEUS HUMAN IGG1 HUMAN
IGG1
Mutations
P01871 -- HOMO SAPIENS HUMAN FAB HEAVY CHAIN HUMAN
FAB HEAVY CHAIN
P01871 -- HOMO SAPIENS HUMAN FAB HEAVY CHAIN HUMAN
FAB HEAVY CHAIN
P01700 -- HOMO SAPIENS HUMAN FAB LIGHT CHAIN HUMAN
FAB LIGHT CHAIN
P01700 -- HOMO SAPIENS HUMAN FAB LIGHT CHAIN HUMAN
FAB LIGHT CHAIN
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402