3CH6

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 3CH6_1

Bioassembly 3CH6_2

Chain 3CH6_A

Chain 3CH6_B

Chain 3CH6_D

Chain 3CH6_E

Spin

Focus

Transparency

More Info

GENERAL

TITLE

CRYSTAL STRUCTURE OF 11BETA-HSD1 DOUBLE MUTANT (L262R, F278E) COMPLEXED WITH (3,3-DIMETHYLPIPERIDIN-1-YL)(6-(3-FLUORO-4- METHYLPHENYL)PYRIDIN-2-YL)METHANONE

DATE LAST MODIFIED

20 Oct 2021

RELEASE

10 Jun 2008

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.35

RESOLUTION RANGE LOW

PUBMED ID

18485702

DOI

10.1016/J.BMCL.2008.04.069

PDBe

LIGANDS

1500968 , 931316

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
O00217	HSD11B1, HSD11, HSD11L	ESCHERICHIA COLI	HUMAN	11-DH 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1; 11-B ...
P19404	HSD11B1, HSD11, HSD11L	ESCHERICHIA COLI	HUMAN	11-DH 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1; 11-B ...
P28845	HSD11B1, HSD11, HSD11L	ESCHERICHIA COLI	HUMAN	11-DH 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1; 11-B ...	Mutations
P28845	HSD11B1, HSD11, HSD11L	ESCHERICHIA COLI	HUMAN	11-DH 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1; 11-B ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402