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GENERAL
TITLE
CRYSTAL STRUCTURE OF P110ALPHA H1047R MUTANT IN COMPLEX WITH NISH2 OF P85ALPHA AND THE DRUG WORTMANNIN
DATE LAST MODIFIED
13 Oct 2021
RELEASE
29 Sept 2009
OBSOLETE
CLASSIFICATION
TRANSFERASE/ONCOPROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1073/PNAS.0908444106
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P42336 PIK3CA SPODOPTERA FRUGIPERDA HUMAN
PI3-KINASE P110 SUBUNIT ALPHA, PTDINS-3-KINASE P11 ...
Mutations
P27986 PIK3R1 SPODOPTERA FRUGIPERDA HOMO SAPIENS -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402