4A55

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4A55_1

Chain 4A55_A

Chain 4A55_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF P110ALPHA IN COMPLEX WITH ISH2 OF P85ALPHA AND THE INHIBITOR PIK-108

DATE LAST MODIFIED

29 Aug 2012

RELEASE

28 Dec 2011

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

I 2 2 2

RESOLUTION RANGE HIGH

3.5

RESOLUTION RANGE LOW

123.41

PUBMED ID

DOI

10.1038/ONC.2011.532

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P42337	--	SPODOPTERA FRUGIPERDA	HOUSE MOUSE	PI3-KINASE SUBUNIT ALPHA, PI3K-ALPHA, PI3KALPHA,PT ...	Mutations
	P27986	--	SPODOPTERA FRUGIPERDA	HUMAN	PI3-KINASE REGULATORY SUBUNIT ALPHA, PI3K REGULATO ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402