4APU

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4APU_A

Chain 4APU_B

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GENERAL

TITLE

PR X-RAY STRUCTURES IN AGONIST CONFORMATIONS REVEAL TWO DIFFERENT MECHANISMS FOR PARTIAL AGONISM IN 11BETA-SUBSTITUTED STEROIDS

DATE LAST MODIFIED

7 Feb 2018

RELEASE

25 Apr 2012

OBSOLETE

CLASSIFICATION

TRANSCRIPTION

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

1.9

RESOLUTION RANGE LOW

70.04

PUBMED ID

DOI

10.1074/JBC.M111.308403

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q183M9	--	ESCHERICHIA COLI	HUMAN	PR, NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 3
	P06401	--	ESCHERICHIA COLI	HUMAN	PR, NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 3	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402