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GENERAL
TITLE
DESIGN AND SYNTHESIS OF BACE1 INHIBITORS WITH IN VIVO BRAIN REDUCTION OF BETA-AMYLOID PEPTIDES (COMPOUND 10)
DATE LAST MODIFIED
14 Feb 2018
RELEASE
17 Oct 2012
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.79
RESOLUTION RANGE LOW
35.87
PUBMED ID
DOI
10.1021/JM3009025
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P56817 -- ESCHERICHIA COLI HUMAN
BACE1, ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402