4AZY

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4AZY_A

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GENERAL

TITLE

DESIGN AND SYNTHESIS OF BACE1 INHIBITORS WITH IN VIVO BRAIN REDUCTION OF BETA-AMYLOID PEPTIDES (COMPOUND 10)

DATE LAST MODIFIED

14 Feb 2018

RELEASE

17 Oct 2012

OBSOLETE

CLASSIFICATION

HYDROLASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.79

RESOLUTION RANGE LOW

35.87

PUBMED ID

DOI

10.1021/JM3009025

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P11889	--	ESCHERICHIA COLI	HUMAN	BACE1, ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402