4C4J

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4C4J_A

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GENERAL

TITLE

STRUCTURE-BASED DESIGN OF ORALLY BIOAVAILABLE PYRROLOPYRIDINE INHIBITORS OF THE MITOTIC KINASE MPS1

DATE LAST MODIFIED

15 Jan 2014

RELEASE

4 Dec 2013

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

I 2 2 2

RESOLUTION RANGE HIGH

2.5

RESOLUTION RANGE LOW

40.65

PUBMED ID

DOI

10.1021/JM401395S

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P33981	--	ESCHERICHIA COLI	HUMAN	PHOSPHOTYROSINE PICKED THREONINE-PROTEIN KINASE, P ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402