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GENERAL
TITLE
STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6-CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS.
DATE LAST MODIFIED
-
RELEASE
10 Dec 2014
OBSOLETE
CLASSIFICATION
CELL CYCLE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.95
RESOLUTION RANGE LOW
50.35
PUBMED ID
DOI
10.1021/JM401555V
PDBe
4CFX
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P24941 | -- | ESCHERICHIA COLI B | HUMAN | CELL DIVISION PROTEIN KINASE 2, P33 PROTEIN KINASE ... | Mutations | |
| Q14568 | -- | ESCHERICHIA COLI B | HUMAN | CYCLIN-A | ||
| P24941 | -- | ESCHERICHIA COLI B | HUMAN | CELL DIVISION PROTEIN KINASE 2, P33 PROTEIN KINASE ... | Mutations | |
| P20248 | -- | ESCHERICHIA COLI B | HUMAN | CYCLIN-A | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402