4DP3

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4DP3_1

Chain 4DP3_A

Chain 4DP3_B

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GENERAL

TITLE

QUADRUPLE MUTANT (N51I+C59R+S108N+I164L) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH P218 AND NADPH

DATE LAST MODIFIED

15 Nov 2017

RELEASE

14 Nov 2012

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE, TRANSFERASE/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.4

RESOLUTION RANGE LOW

19.9

PUBMED ID

DOI

10.1073/PNAS.1204556109

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q5SLQ0	DHFR-TS, V1/S	ESCHERICHIA COLI	PLASMODIUM FALCIPARUM	--
	P80373	DHFR-TS, V1/S	ESCHERICHIA COLI	PLASMODIUM FALCIPARUM	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402