4DTG

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4DTG_1

Chain 4DTG_H

Chain 4DTG_K

Chain 4DTG_L

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GENERAL

TITLE

HEMOSTATIC EFFECT OF A MONOCLONAL ANTIBODY MAB 2021 BLOCKING THE INTERACTION BETWEEN FXA AND TFPI IN A RABBIT HEMOPHILIA MODEL

DATE LAST MODIFIED

7 Mar 2018

RELEASE

13 Jun 2012

OBSOLETE

CLASSIFICATION

BLOOD CLOTTING INHIBITOR/IMMUNE SYSTEM

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

I 2 2 2

RESOLUTION RANGE HIGH

1.8

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1182/BLOOD-2012-01-401620

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
	--	HOMO SAPIENS	HUMAN	--
P10646	LACI, TFPI, TFPI (AMINO ACIDS 119-178), TFPI1	ESCHERICHIA COLI	HUMAN	TFPI, EXTRINSIC PATHWAY INHIBITOR, EPI, LIPOPROTEI ...	Mutations
	--	HOMO SAPIENS	HUMAN	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402