4E06

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4E06_1

Chain 4E06_H

Chain 4E06_I

Chain 4E06_L

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GENERAL

TITLE

ANOPHELIN FROM THE MALARIA VECTOR INHIBITS THROMBIN THROUGH A NOVEL REVERSE-BINDING MECHANISM

DATE LAST MODIFIED

29 Jul 2020

RELEASE

5 Dec 2012

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

H 3 2

RESOLUTION RANGE HIGH

3.196

RESOLUTION RANGE LOW

46.833

PUBMED ID

DOI

10.1073/PNAS.1211614109

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
A6TED5	--	--	HUMAN	COAGULATION FACTOR II
Q9NJS1	ANOPHELIN	ESCHERICHIA COLI	NEW WORLD MALARIA MOSQUITO	--
P00734	--	--	HUMAN	COAGULATION FACTOR II	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402