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3D Structure View

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GENERAL
TITLE
DISCOVERY OF SMALL MOLECULES THAT BIND TO K-RAS AND INHIBIT SOS- MEDIATED ACTIVATION
DATE LAST MODIFIED
25 Jul 2012
RELEASE
23 May 2012
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 63
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1002/ANIE.201201358
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI HUMAN
K-RAS 2, KI-RAS, C-K-RAS, C-KI-RAS, GTPASE KRAS, N ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402