4EQZ logo

4EQZ

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN DOT1L IN COMPLEX WITH INHIBITOR FED2
DATE LAST MODIFIED
16 May 2018
RELEASE
2 May 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 65
RESOLUTION RANGE HIGH
2.15
RESOLUTION RANGE LOW
132.679
PUBMED ID
DOI
10.1038/NCOMMS2304
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q8TEK3 DOT1L, KIAA1814, KMT4 ESCHERICHIA COLI HUMAN
DOT1-LIKE PROTEIN, HISTONE H3-K79 METHYLTRANSFERAS ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402