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GENERAL
TITLE
THE BICYCLIC INTERMEDIATE STRUCTURE PROVIDES INSIGHTS INTO THE DESUCCINYLATION MECHANISM OF SIRT5
DATE LAST MODIFIED
15 Nov 2017
RELEASE
20 Jun 2012
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.7
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1074/JBC.M112.384511
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q9NXA8 SIR2L5, SIRT5 ESCHERICHIA COLI HUMAN
SIR2-LIKE PROTEIN 5
Mutations
Q9NXA8 SIR2L5, SIRT5 ESCHERICHIA COLI HUMAN
SIR2-LIKE PROTEIN 5
Mutations
P68431 -- -- HUMAN
HISTONE H3/A, HISTONE H3/B, HISTONE H3/C, HISTONE ...
Mutations
P68431 -- -- HUMAN
HISTONE H3/A, HISTONE H3/B, HISTONE H3/C, HISTONE ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402