4F6U

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4F6U_1

Chain 4F6U_A

Chain 4F6U_B

Spin

Focus

Transparency

More Info

GENERAL

TITLE

CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 5 (1-[3- TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[3-(MORPHOLIN-4-YL) PROPYL]UREA)

DATE LAST MODIFIED

1 Apr 2015

RELEASE

1 May 2013

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSCRIPTION/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.1

RESOLUTION RANGE LOW

85.61

PUBMED ID

23630251

DOI

10.1073/PNAS.1305378110

PDBe

4F6U

LIGANDS

2855234 , 173 , 230 , , 2694652

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P49336	CDK8	SPODOPTERA FRUGIPERDA	HUMAN	CELL DIVISION PROTEIN KINASE 8, MEDIATOR COMPLEX S ...	Mutations
	P24863	CCNC	SPODOPTERA FRUGIPERDA	HUMAN	SRB11 HOMOLOG, HSRB11	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402