4F70

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4F70_1

Chain 4F70_A

Chain 4F70_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 4 (1-[3- TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[2-(MORPHOLIN-4-YL) ETHYL]UREA)

DATE LAST MODIFIED

1 Apr 2015

RELEASE

1 May 2013

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSCRIPTION/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

RESOLUTION RANGE LOW

85.52

PUBMED ID

23630251

DOI

10.1073/PNAS.1305378110

PDBe

4F70

LIGANDS

120035 , 230

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P50264	CDK8	SPODOPTERA FRUGIPERDA	HUMAN	CELL DIVISION PROTEIN KINASE 8, MEDIATOR COMPLEX S ...
	P50264	CCNC	SPODOPTERA FRUGIPERDA	HUMAN	SRB11 HOMOLOG, HSRB11

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402