4FDH

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4FDH_1

Bioassembly 4FDH_2

Chain 4FDH_A

Chain 4FDH_B

Chain 4FDH_C

Chain 4FDH_D

Chain 4FDH_E

Chain 4FDH_F

Chain 4FDH_G

Chain 4FDH_H

Chain 4FDH_I

Chain 4FDH_J

Chain 4FDH_K

Chain 4FDH_L

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GENERAL

TITLE

STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH FADROZOLE

DATE LAST MODIFIED

13 Feb 2013

RELEASE

30 Jan 2013

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.71

RESOLUTION RANGE LOW

49.19

PUBMED ID

23322723

DOI

10.1210/ME.2012-1287

PDBe

4FDH

LIGANDS

1041891 , 2693499

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P55273	ALDOSTERONE SYNTHASE, CYP11B2	ESCHERICHIA COLI	HUMAN	ALDOSTERONE SYNTHASE, ALDOS, ALDOSTERONE-SYNTHESIZ ...
P00641	ALDOSTERONE SYNTHASE, CYP11B2	ESCHERICHIA COLI	HUMAN	ALDOSTERONE SYNTHASE, ALDOS, ALDOSTERONE-SYNTHESIZ ...
P16298	ALDOSTERONE SYNTHASE, CYP11B2	ESCHERICHIA COLI	HUMAN	ALDOSTERONE SYNTHASE, ALDOS, ALDOSTERONE-SYNTHESIZ ...
Q96HY7	ALDOSTERONE SYNTHASE, CYP11B2	ESCHERICHIA COLI	HUMAN	ALDOSTERONE SYNTHASE, ALDOS, ALDOSTERONE-SYNTHESIZ ...
P19099	ALDOSTERONE SYNTHASE, CYP11B2	ESCHERICHIA COLI	HUMAN	ALDOSTERONE SYNTHASE, ALDOS, ALDOSTERONE-SYNTHESIZ ...	Mutations
P19099	ALDOSTERONE SYNTHASE, CYP11B2	ESCHERICHIA COLI	HUMAN	ALDOSTERONE SYNTHASE, ALDOS, ALDOSTERONE-SYNTHESIZ ...	Mutations
P19099	ALDOSTERONE SYNTHASE, CYP11B2	ESCHERICHIA COLI	HUMAN	ALDOSTERONE SYNTHASE, ALDOS, ALDOSTERONE-SYNTHESIZ ...	Mutations
Q96HY7	ALDOSTERONE SYNTHASE, CYP11B2	ESCHERICHIA COLI	HUMAN	ALDOSTERONE SYNTHASE, ALDOS, ALDOSTERONE-SYNTHESIZ ...
P63098	ALDOSTERONE SYNTHASE, CYP11B2	ESCHERICHIA COLI	HUMAN	ALDOSTERONE SYNTHASE, ALDOS, ALDOSTERONE-SYNTHESIZ ...
P19099	ALDOSTERONE SYNTHASE, CYP11B2	ESCHERICHIA COLI	HUMAN	ALDOSTERONE SYNTHASE, ALDOS, ALDOSTERONE-SYNTHESIZ ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402