4FHH

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4FHH_1

Chain 4FHH_A

Chain 4FHH_B

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GENERAL

TITLE

DEVELOPMENT OF SYNTHETICALLY ACCESSIBLE NON-SECOSTEROIDAL HYBRID MOLECULES COMBINING VITAMIN D RECEPTOR AGONISM AND HISTONE DEACETYLASE INHIBITION

DATE LAST MODIFIED

10 Mar 2021

RELEASE

19 Sept 2012

OBSOLETE

CLASSIFICATION

TRANSCRIPTION/PROTEIN BINDING/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 65 2 2

RESOLUTION RANGE HIGH

2.33

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1016/J.CHEMBIOL.2012.05.024

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q9UNL4	VDRA, NR1I1A, VDR	ESCHERICHIA COLI	LEOPARD DANIO,ZEBRA DANIO,ZEBRA FISH	VDR-A, 1,25-DIHYDROXYVITAMIN D3 RECEPTOR A, NUCLEA ...
	Q9UNL4	--	--	HUMAN	NCOA-2, CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75, ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402