4FI7

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4FI7_1

Chain 4FI7_A

Chain 4FI7_B

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GENERAL

TITLE

KINETIC STABILIZATION OF TRANSTHYRETIN THROUGH COVALENT MODIFICATION OF K15 BY 3-(5-(3,5-DICHLORO-4-HYDROXYPHENYL)-1,3,4-OXADIAZOL-2-YL)- BENZENESULFONAMIDE

DATE LAST MODIFIED

29 Jan 2014

RELEASE

20 Feb 2013

OBSOLETE

CLASSIFICATION

HORMONE/HORMONE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 2

RESOLUTION RANGE HIGH

1.4

RESOLUTION RANGE LOW

85.76

PUBMED ID

23350654

DOI

10.1021/JA311729D

PDBe

4FI7

LIGANDS

2972116

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P02766	TTR, PALB	ESCHERICHIA COLI	HUMAN	ATTR, PREALBUMIN, TBPA	Mutations
	P02766	TTR, PALB	ESCHERICHIA COLI	HUMAN	ATTR, PREALBUMIN, TBPA	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402