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GENERAL
TITLE
CRYSTAL STRUCTURE OF SPLEEN TYROSINE KINASE COMPLEXED WITH [6-((S)-2- METHYL-PYRROLIDIN-1-YL)-PYRIDIN-2-YL]-(6-PHENYL-IMIDAZO[1,2- B]PYRIDAZIN-8-YL)-AMINE
DATE LAST MODIFIED
17 Jul 2019
RELEASE
30 Jan 2013
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.85
RESOLUTION RANGE LOW
30.994
PUBMED ID
23151054
DOI
10.1021/JM301367C
PDBe
PDBe logo  4FZ6
LIGANDS
131378

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P43405 SYK SPODOPTERA FRUGIPERDA HUMAN
SPLEEN TYROSINE KINASE, P72-SYK
 Mutations
Chains Per Page:
1-1 of 1
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402