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GENERAL
TITLE
CRYSTAL STRUCTURE OF INHIBITORY PROTEIN SOCS3 IN COMPLEX WITH JAK2 KINASE DOMAIN AND FRAGMENT OF GP130 INTRACELLULAR DOMAIN
DATE LAST MODIFIED
13 Jun 2018
RELEASE
6 Mar 2013
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 65
RESOLUTION RANGE HIGH
3.9
RESOLUTION RANGE LOW
45.584
PUBMED ID
DOI
10.1038/NSMB.2519
PDBe
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q7NDN8 | JAK2, MCG_9104 | SPODOPTERA FRUGIPERDA | MOUSE | -- | ||
| Q9KV17 | JAK2, MCG_9104 | SPODOPTERA FRUGIPERDA | MOUSE | -- | ||
| Q7NDN8 | JAK2, MCG_9104 | SPODOPTERA FRUGIPERDA | MOUSE | -- | ||
| Q9JYL2 | JAK2, MCG_9104 | SPODOPTERA FRUGIPERDA | MOUSE | -- | ||
| O35718 | SOCS3, CIS3, CISH3 | ESCHERICHIA COLI | MOUSE, MOUSE | SOCS-3,CYTOKINE-INDUCIBLE SH2 PROTEIN 3,CIS-3,PROT ... | Mutations | |
| P32927 | SOCS3, CIS3, CISH3 | ESCHERICHIA COLI | MOUSE, MOUSE | SOCS-3,CYTOKINE-INDUCIBLE SH2 PROTEIN 3,CIS-3,PROT ... | ||
| O35718 | SOCS3, CIS3, CISH3 | ESCHERICHIA COLI | MOUSE, MOUSE | SOCS-3,CYTOKINE-INDUCIBLE SH2 PROTEIN 3,CIS-3,PROT ... | Mutations | |
| O35718 | SOCS3, CIS3, CISH3 | ESCHERICHIA COLI | MOUSE, MOUSE | SOCS-3,CYTOKINE-INDUCIBLE SH2 PROTEIN 3,CIS-3,PROT ... | Mutations | |
| P15291 | -- | -- | MOUSE | IL-6RB,INTERLEUKIN-6 SIGNAL TRANSDUCER,MEMBRANE GL ... | ||
| P15291 | -- | -- | MOUSE | IL-6RB,INTERLEUKIN-6 SIGNAL TRANSDUCER,MEMBRANE GL ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402