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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE HIGH AFFINITY HETERODIMER OF HIF2 ALPHA AND ARNT C-TERMINAL PAS DOMAINS IN COMPLEX WITH AN INACTIVE BENZOXADIAZOLE ANTAGONIST
DATE LAST MODIFIED
30 May 2018
RELEASE
3 Apr 2013
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.72
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM301847Z

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q99814 BHLHE73, EPAS1, HIF2, HIF2A, MOP2, PASD2 ESCHERICHIA COLI HUMAN
EPAS-1, BASIC-HELIX-LOOP-HELIX-PAS PROTEIN MOP2, C ...
Mutations
P27540 ARNT, BHLHE2 ESCHERICHIA COLI HUMAN
ARNT PROTEIN, CLASS E BASIC HELIX-LOOP-HELIX PROTE ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402