4GS9

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4GS9_1

Chain 4GS9_A

Chain 4GS9_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF THE HIGH AFFINITY HETERODIMER OF HIF2 ALPHA AND ARNT C-TERMINAL PAS DOMAINS IN COMPLEX WITH AN INACTIVE BENZOXADIAZOLE ANTAGONIST

DATE LAST MODIFIED

30 May 2018

RELEASE

3 Apr 2013

OBSOLETE

CLASSIFICATION

TRANSCRIPTION

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

1.72

RESOLUTION RANGE LOW

PUBMED ID

23363003

DOI

10.1021/JM301847Z

PDBe

4GS9

LIGANDS

1213710 , 2695187

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P09467	BHLHE73, EPAS1, HIF2, HIF2A, MOP2, PASD2	ESCHERICHIA COLI	HUMAN	EPAS-1, BASIC-HELIX-LOOP-HELIX-PAS PROTEIN MOP2, C ...
	P09467	ARNT, BHLHE2	ESCHERICHIA COLI	HUMAN	ARNT PROTEIN, CLASS E BASIC HELIX-LOOP-HELIX PROTE ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402