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GENERAL
TITLE
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH (E)- 3-(3-CHLORO-5-(4-CHLORO-2-(2-(2,4-DIOXO-3,4- DIHYDROPYRIMIDIN-1(2H)- YL)ETHOXY)PHENOXY)PHENYL)ACRYLONITRILE (JLJ494), A NON-NUCLEOSIDE INHIBITOR
DATE LAST MODIFIED
15 Nov 2017
RELEASE
5 Dec 2012
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.85
RESOLUTION RANGE LOW
36.64
PUBMED ID
DOI
10.1021/JA3092642
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P03366 P66 RT ESCHERICHIA COLI HIV-1
GAG-POL POLYPROTEIN
Mutations
P03366 P51 RT ESCHERICHIA COLI HIV-1
GAG-POL POLYPROTEIN
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402