4H4M

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4H4M_1

Chain 4H4M_A

Chain 4H4M_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH (E)- 3-(3-CHLORO-5-(4-CHLORO-2-(2-(2,4-DIOXO-3,4- DIHYDROPYRIMIDIN-1(2H)- YL)ETHOXY)PHENOXY)PHENYL)ACRYLONITRILE (JLJ494), A NON-NUCLEOSIDE INHIBITOR

DATE LAST MODIFIED

15 Nov 2017

RELEASE

5 Dec 2012

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

2.85

RESOLUTION RANGE LOW

36.64

PUBMED ID

23163887

DOI

10.1021/JA3092642

PDBe

4H4M

LIGANDS

290690 , 230

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q45894	P66 RT	ESCHERICHIA COLI	HIV-1	GAG-POL POLYPROTEIN
	Q45894	P51 RT	ESCHERICHIA COLI	HIV-1	GAG-POL POLYPROTEIN

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402