4H4O logo

4H4O

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH (E)-3-(3-(2-(2-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)ETHOXY)- 4- FLUOROPHENOXY)-5-FLUOROPHENYL)ACRYLONITRILE (JLJ506), A NON- NUCLEOSIDE INHIBITOR
DATE LAST MODIFIED
15 Nov 2017
RELEASE
5 Dec 2012
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
41.722
PUBMED ID
DOI
10.1021/JA3092642
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P03366 P66 RT ESCHERICHIA COLI HIV-1
GAG-POL POLYPROTEIN
Mutations
P03366 P51 RT ESCHERICHIA COLI HIV-1
GAG-POL POLYPROTEIN
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402