4H76

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4H76_A

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GENERAL

TITLE

CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN MMP12 IN COMPLEX WITH A BROAD SPECTRUM HYDROXAMATE INHIBITOR

DATE LAST MODIFIED

12 Aug 2015

RELEASE

24 Apr 2013

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 2

RESOLUTION RANGE HIGH

1.5

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1016/J.JSB.2013.03.015

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P39900	HME, MMP12	ESCHERICHIA COLI	HUMAN	MME, MACROPHAGE ELASTASE, ME, HME, MATRIX METALLOP ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402