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GENERAL
TITLE
HUMAN 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 IN COMPLEX WITH AN ORALLY BIOAVAILABLE ACIDIC INHIBITOR AZD4017.
DATE LAST MODIFIED
24 Jan 2018
RELEASE
17 Oct 2012
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
2.73
RESOLUTION RANGE LOW
54.5
PUBMED ID
DOI
10.1021/JM300592R

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P28845 HSD11B1, HSD11, HSD11L ESCHERICHIA COLI HUMAN
11-BETA-HYDROXYSTEROID DEHYDROGENASE 1, 11-DH, 11- ...
Mutations
P28845 HSD11B1, HSD11, HSD11L ESCHERICHIA COLI HUMAN
11-BETA-HYDROXYSTEROID DEHYDROGENASE 1, 11-DH, 11- ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402