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3D Structure View

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GENERAL
TITLE
HUMAN CONSTITUTIVE 20S PROTEASOME IN COMPLEX WITH CARFILZOMIB
DATE LAST MODIFIED
18 Feb 2015
RELEASE
11 Feb 2015
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.89
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.STR.2014.11.017
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P49721 -- -- HUMAN
MACROPAIN SUBUNIT C7-I, MULTICATALYTIC ENDOPEPTIDA ...
Mutations
P20618 -- -- HUMAN
MACROPAIN SUBUNIT C5, MULTICATALYTIC ENDOPEPTIDASE ...
Mutations
Q9BVC4 -- -- HUMAN
26 KDA PROSOMAL PROTEIN, HSBPROS26, PROS-26, MACRO ...
P42345 -- -- HUMAN
MACROPAIN EPSILON CHAIN, MULTICATALYTIC ENDOPEPTID ...
Q9Y468 -- -- HUMAN
27 KDA PROSOMAL PROTEIN, PROS-27, P27K, MACROPAIN ...
P25787 -- -- HUMAN
MACROPAIN SUBUNIT C3, MULTICATALYTIC ENDOPEPTIDASE ...
Mutations
P0AFZ3 -- -- HUMAN
MACROPAIN SUBUNIT C9, MULTICATALYTIC ENDOPEPTIDASE ...
P43490 -- -- HUMAN
PROTEASOME SUBUNIT RC6-1, PROTEASOME SUBUNIT XAPC7 ...
Q746I8 -- -- HUMAN
MACROPAIN ZETA CHAIN, MULTICATALYTIC ENDOPEPTIDASE ...
P25786 -- -- HUMAN
30 KDA PROSOMAL PROTEIN, PROS-30, MACROPAIN SUBUNI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402