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GENERAL
TITLE
CRYSTAL STRUCTURE ANALYSIS OF CRUZAIN WITH THREE FRAGMENTS: 1 (N-(1H- BENZIMIDAZOL-2-YL)-1,3-DIMETHYL-PYRAZOLE-4-CARBOXAMIDE), 6 (2-AMINO- 4,6-DIFLUOROBENZOTHIAZOLE) AND 9 (N-(1H-BENZIMIDAZOL-2-YL)-3-(4- FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE).
DATE LAST MODIFIED
22 Nov 2017
RELEASE
8 Apr 2015
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43 21 2
RESOLUTION RANGE HIGH
3.27
RESOLUTION RANGE LOW
30
PUBMED ID
-
DOI
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P60043 -- ESCHERICHIA COLI TRYPANOSOMA CRUZI
CRUZAINE,MAJOR CYSTEINE PROTEINASE
P25779 -- ESCHERICHIA COLI TRYPANOSOMA CRUZI
CRUZAINE,MAJOR CYSTEINE PROTEINASE
Mutations
Q96P20 -- ESCHERICHIA COLI TRYPANOSOMA CRUZI
CRUZAINE,MAJOR CYSTEINE PROTEINASE
P25779 -- ESCHERICHIA COLI TRYPANOSOMA CRUZI
CRUZAINE,MAJOR CYSTEINE PROTEINASE
Mutations
P25779 -- ESCHERICHIA COLI TRYPANOSOMA CRUZI
CRUZAINE,MAJOR CYSTEINE PROTEINASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402