4W5O

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4W5O_A

Chain 4W5O_B

Chain 4W5O_D

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GENERAL

TITLE

THE CRYSTAL STRUCTURE OF HUMAN ARGONAUTE2 BOUND TO A GUIDE AND TARGET RNA CONTAINING SEED PAIRING FROM 2-9

DATE LAST MODIFIED

22 Nov 2017

RELEASE

12 Nov 2014

OBSOLETE

CLASSIFICATION

HYDROLASE/RNA

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

1.8

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1126/SCIENCE.1258040

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
Q9UKV8	AGO2, EIF2C2	SPODOPTERA FRUGIPERDA	HUMAN	HAGO2,ARGONAUTE RISC CATALYTIC COMPONENT 2,EUKARYO ...	Mutations
	--	--	SYNTHETIC CONSTRUCT	--
	--	--	SYNTHETIC CONSTRUCT	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402