4WQ6

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4WQ6_1

Chain 4WQ6_A

Chain 4WQ6_B

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GENERAL

TITLE

THE CRYSTAL STRUCTURE OF HUMAN NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) IN COMPLEX WITH N-(4-{(S)-[1-(2-METHYLPROPYL)PIPERIDIN-4- YL]SULFINYL}BENZYL)FURO[2,3-C]PYRIDINE-2-CARBOXAMIDE INHIBITOR (COMPOUND 21)

DATE LAST MODIFIED

RELEASE

11 Feb 2015

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

1.72

RESOLUTION RANGE LOW

PUBMED ID

25556090

DOI

10.1016/J.BMCL.2014.12.026

PDBe

4WQ6

LIGANDS

2870479 , 230 , 2760764

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q9I0A0	NAMPT, PBEF, PBEF1	ESCHERICHIA COLI	HUMAN	NAMPT,PRE-B-CELL COLONY-ENHANCING FACTOR 1,PRE-B C ...
	P93836	NAMPT, PBEF, PBEF1	ESCHERICHIA COLI	HUMAN	NAMPT,PRE-B-CELL COLONY-ENHANCING FACTOR 1,PRE-B C ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402