4WVD

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4WVD_1

Bioassembly 4WVD_2

Chain 4WVD_A

Chain 4WVD_B

Chain 4WVD_C

Chain 4WVD_D

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GENERAL

TITLE

IDENTIFICATION OF A NOVEL FXR LIGAND THAT REGULATES METABOLISM

DATE LAST MODIFIED

27 Sept 2017

RELEASE

11 Feb 2015

OBSOLETE

CLASSIFICATION

TRANSCRIPTION

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

I 21 21 21

RESOLUTION RANGE HIGH

2.3

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1038/NCOMMS2924

PDBe

LIGANDS

Chains

Target Protein	Gene	Expression System	Organism	Synonims
K9N5Q8	NR1H4, BAR, FXR, HRR1, RIP14	ESCHERICHIA COLI BL21(DE3)	HUMAN	FARNESOID X-ACTIVATED RECEPTOR,FARNESOL RECEPTOR H ...
K9N5Q8	NR1H4, BAR, FXR, HRR1, RIP14	ESCHERICHIA COLI BL21(DE3)	HUMAN	FARNESOID X-ACTIVATED RECEPTOR,FARNESOL RECEPTOR H ...
B8XX90	--	--	HUMAN	N-COR1
K9N5Q8	--	--	HUMAN	N-COR1

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402