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GENERAL
TITLE
X-RAY CRYSTAL STRUCTURE OF THE ORALLY AVAILABLE AMINOPEPTIDASE INHIBITOR, TOSEDOSTAT, BOUND TO THE M17 LEUCYL AMINOPEPTIDASE FROM P. FALCIPARUM
DATE LAST MODIFIED
1 Jan 2020
RELEASE
18 Feb 2015
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.729
RESOLUTION RANGE LOW
48.75
PUBMED ID
DOI
10.1002/PROT.24771
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
A0R2I8 LAP, PF14_0439 ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) --
P06873 LAP, PF14_0439 ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) --
Q9LCV9 LAP, PF14_0439 ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) --
Q9LCV9 LAP, PF14_0439 ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) --
Q9LCV9 LAP, PF14_0439 ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) --
A0R2I8 LAP, PF14_0439 ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) --
Q9JJX7 LAP, PF14_0439 ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) --
Q9LCV9 LAP, PF14_0439 ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) --
Q9JJX7 LAP, PF14_0439 ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) --
P19909 LAP, PF14_0439 ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402