4XV2

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4XV2_1

Chain 4XV2_A

Chain 4XV2_B

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GENERAL

TITLE

B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH DABRAFENIB

DATE LAST MODIFIED

4 Nov 2015

RELEASE

28 Oct 2015

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.5

RESOLUTION RANGE LOW

76.114

PUBMED ID

DOI

10.1038/NATURE14982

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q9BPX1	BRAF, BRAF1, RAFB1	ESCHERICHIA COLI	HUMAN	PROTO-ONCOGENE B-RAF,P94,V-RAF MURINE SARCOMA VIRA ...
	P15056	BRAF, BRAF1, RAFB1	ESCHERICHIA COLI	HUMAN	PROTO-ONCOGENE B-RAF,P94,V-RAF MURINE SARCOMA VIRA ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402