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GENERAL
TITLE
CRYSTAL STRUCTURE OF COT KINASE DOMAIN IN COMPLEX WITH 5-(2-AMINO-5- (QUINOLIN-3-YL)PYRIDIN-3-YL)-1,3,4-OXADIAZOLE-2(3H)-THIONE
DATE LAST MODIFIED
16 Oct 2019
RELEASE
6 May 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31
RESOLUTION RANGE HIGH
2.89
RESOLUTION RANGE LOW
88.31
PUBMED ID
DOI
10.1074/JBC.M115.648097
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P0CH43 MAP3K8, COT, ESTF SPODOPTERA FRUGIPERDA HUMAN
CANCER OSAKA THYROID ONCOGENE,PROTO-ONCOGENE C-COT ...
Q15858 MAP3K8, COT, ESTF SPODOPTERA FRUGIPERDA HUMAN
CANCER OSAKA THYROID ONCOGENE,PROTO-ONCOGENE C-COT ...
O34539 MAP3K8, COT, ESTF SPODOPTERA FRUGIPERDA HUMAN
CANCER OSAKA THYROID ONCOGENE,PROTO-ONCOGENE C-COT ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402