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GENERAL
TITLE
ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH SQUARAMIDE COMPOUND 14 (N-[3,4-DIOXO-2-(4-{[4-(TRIFLUOROMETHYL)BENZYL]AMINO}PIPERIDIN-1-YL) CYCLOBUT-1-EN-1-YL]-3,5-DIMETHYL-1,2-OXAZOLE-4-SULFONAMIDE)
DATE LAST MODIFIED
25 Dec 2019
RELEASE
11 Mar 2015
OBSOLETE
CLASSIFICATION
TRANSCRIPTION/TRANSCRIPTION INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
3.8
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.5B00050

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P09099 RPOA, ECE24377A_3778 ESCHERICHIA COLI #1/H766 ESCHERICHIA COLI O139:H28 (STRAIN E24377A /
RNAP SUBUNIT ALPHA,RNA POLYMERASE SUBUNIT ALPHA,TR ...
Q12959 RPOA, ECE24377A_3778 ESCHERICHIA COLI #1/H766 ESCHERICHIA COLI O139:H28 (STRAIN E24377A /
RNAP SUBUNIT ALPHA,RNA POLYMERASE SUBUNIT ALPHA,TR ...
P00918 RPOB, ECE24377A_4528 ESCHERICHIA COLI #1/H766 ESCHERICHIA COLI O139:H28 (STRAIN E24377A /
RNAP SUBUNIT BETA,RNA POLYMERASE SUBUNIT BETA,TRAN ...
P04925 RPOC, ECE24377A_4529 ESCHERICHIA COLI #1/H766 ESCHERICHIA COLI O139:H28 (STRAIN E24377A /
RNAP SUBUNIT BETA',RNA POLYMERASE SUBUNIT BETA',TR ...
P06463 RPOZ, ECE24377A_4152 ESCHERICHIA COLI #1/H766 ESCHERICHIA COLI O139:H28 (STRAIN E24377A /
RNAP OMEGA SUBUNIT,RNA POLYMERASE OMEGA SUBUNIT,TR ...
P17312 RPOD, ALT, B3067, JW3039 ESCHERICHIA COLI #1/H766 ESCHERICHIA COLI (STRAIN K12)
SIGMA-70
Q12959 RPOA, ECE24377A_3778 ESCHERICHIA COLI #1/H766 ESCHERICHIA COLI O139:H28 (STRAIN E24377A /
RNAP SUBUNIT ALPHA,RNA POLYMERASE SUBUNIT ALPHA,TR ...
Q12959 RPOA, ECE24377A_3778 ESCHERICHIA COLI #1/H766 ESCHERICHIA COLI O139:H28 (STRAIN E24377A /
RNAP SUBUNIT ALPHA,RNA POLYMERASE SUBUNIT ALPHA,TR ...
A7ZUK1 RPOB, ECE24377A_4528 ESCHERICHIA COLI #1/H766 ESCHERICHIA COLI O139:H28 (STRAIN E24377A /
RNAP SUBUNIT BETA,RNA POLYMERASE SUBUNIT BETA,TRAN ...
Mutations
P06463 RPOC, ECE24377A_4529 ESCHERICHIA COLI #1/H766 ESCHERICHIA COLI O139:H28 (STRAIN E24377A /
RNAP SUBUNIT BETA',RNA POLYMERASE SUBUNIT BETA',TR ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402