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GENERAL
TITLE
(R)-2-PHENYLPYRROLIDINE SUBSTITUTE IMIDAZOPYRIDAZINES: A NEW CLASS OF POTENT AND SELECTIVE PAN-TRK INHIBITORS
DATE LAST MODIFIED
-
RELEASE
3 Jun 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32
RESOLUTION RANGE HIGH
1.92
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.5B00050

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P0C6Y3 NTRK3, TRKC SPODOPTERA FRUGIPERDA HUMAN
GP145-TRKC,TRK-C,NEUROTROPHIC TYROSINE KINASE RECE ...
P17802 NTRK3, TRKC SPODOPTERA FRUGIPERDA HUMAN
GP145-TRKC,TRK-C,NEUROTROPHIC TYROSINE KINASE RECE ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402