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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN PHOSPHORYLATED IRE1ALPHA IN COMPLEX WITH A TYPE III KINASE INHIBITOR (GSK2850163A)
DATE LAST MODIFIED
-
RELEASE
11 Nov 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
2.45
RESOLUTION RANGE LOW
29.182
PUBMED ID
DOI
10.1124/MOL.115.100917
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P0A3C9 ERN1, IRE1 SPODOPTERA FRUGIPERDA HUMAN
ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1,INOSI ...
O75460 ERN1, IRE1 SPODOPTERA FRUGIPERDA HUMAN
ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1,INOSI ...
Mutations
O75460 ERN1, IRE1 SPODOPTERA FRUGIPERDA HUMAN
ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1,INOSI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402