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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE JAK3 KINASE DOMAIN COVALENTLY BOUND TO N-(3- (((5-CHLORO-2-((2-METHOXY-4-(4-METHYLPIPERAZIN-1-YL)PHENYL)AMINO) PYRIMIDIN-4-YL)AMINO)METHYL)PHENYL)ACRYLAMIDE
DATE LAST MODIFIED
-
RELEASE
10 Feb 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
92.91
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.5B00710

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P02070 JAK3 TRICHOPLUSIA NI HUMAN
JANUS KINASE 3,JAK-3,LEUKOCYTE JANUS KINASE,L-JAK
P0DTC2 JAK3 TRICHOPLUSIA NI HUMAN
JANUS KINASE 3,JAK-3,LEUKOCYTE JANUS KINASE,L-JAK
P02070 JAK3 TRICHOPLUSIA NI HUMAN
JANUS KINASE 3,JAK-3,LEUKOCYTE JANUS KINASE,L-JAK
P0DTC2 JAK3 TRICHOPLUSIA NI HUMAN
JANUS KINASE 3,JAK-3,LEUKOCYTE JANUS KINASE,L-JAK
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402