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GENERAL
TITLE
VX-680/MK-0457 BINDS TO HUMAN ABL1 ALSO IN INACTIVE DFG CONFORMATIONS.
DATE LAST MODIFIED
19 Oct 2016
RELEASE
14 Sept 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
50
PUBMED ID
-
DOI
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P11498 ABL1, ABL, JTK7 ESCHERICHIA COLI BL21(DE3) HUMAN
ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1,A ...
P54760 ABL1, ABL, JTK7 ESCHERICHIA COLI BL21(DE3) HUMAN
ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1,A ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402