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GENERAL
TITLE
CASPASE-7 VARIANT 1 (V1) WITH REPROGRAMMED SUBSTRATE SPECIFICITY DUE TO Y230A/W232M/S234N SUBSTITUTIONS, BOUND TO DEVD INHIBITOR.
DATE LAST MODIFIED
25 Dec 2019
RELEASE
20 Apr 2016
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACSCHEMBIO.5B00971
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P55210 CASP7, MCH3 ESCHERICHIA COLI BL21(DE3) HUMAN
CASP-7,APOPTOTIC PROTEASE MCH-3,CMH-1,ICE-LIKE APO ...
Mutations
P55210 CASP7, MCH3 ESCHERICHIA COLI BL21(DE3) HUMAN
CASP-7,APOPTOTIC PROTEASE MCH-3,CMH-1,ICE-LIKE APO ...
Mutations
P55210 CASP7, MCH3 ESCHERICHIA COLI BL21(DE3) HUMAN
CASP-7,APOPTOTIC PROTEASE MCH-3,CMH-1,ICE-LIKE APO ...
Mutations
P55210 CASP7, MCH3 ESCHERICHIA COLI BL21(DE3) HUMAN
CASP-7,APOPTOTIC PROTEASE MCH-3,CMH-1,ICE-LIKE APO ...
Mutations
-- -- SYNTHETIC CONSTRUCT --
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NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402