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3D Structure View

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GENERAL
TITLE
EED IN COMPLEX WITH AN ALLOSTERIC PRC2 INHIBITOR
DATE LAST MODIFIED
5 Apr 2017
RELEASE
1 Feb 2017
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
2.49
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1038/NCHEMBIO.2304
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O75530 EED ESCHERICHIA COLI HUMAN
HEED,WD PROTEIN ASSOCIATING WITH INTEGRIN CYTOPLAS ...
Mutations
O75530 EED ESCHERICHIA COLI HUMAN
HEED,WD PROTEIN ASSOCIATING WITH INTEGRIN CYTOPLAS ...
Mutations
Q15910 -- -- HUMAN
ENX-1,ENHANCER OF ZESTE HOMOLOG 2,LYSINE N-METHYLT ...
Mutations
Q15910 -- -- HUMAN
ENX-1,ENHANCER OF ZESTE HOMOLOG 2,LYSINE N-METHYLT ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402