5IAW

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5IAW_1

Bioassembly 5IAW_2

Chain 5IAW_A

Chain 5IAW_B

Chain 5IAW_C

Chain 5IAW_D

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GENERAL

TITLE

NOVEL NATURAL FXR MODULATOR WITH A UNIQUE BINDING MODE

DATE LAST MODIFIED

3 May 2017

RELEASE

8 Mar 2017

OBSOLETE

CLASSIFICATION

TRANSCRIPTION

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 2 1

RESOLUTION RANGE HIGH

2.58

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1002/CBIC.201700059

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
Q96RI1	NR1H4, BAR, FXR, HRR1, RIP14	ESCHERICHIA COLI	HUMAN	FARNESOID X-ACTIVATED RECEPTOR,FARNESOL RECEPTOR H ...	Mutations
Q96RI1	NR1H4, BAR, FXR, HRR1, RIP14	ESCHERICHIA COLI	HUMAN	FARNESOID X-ACTIVATED RECEPTOR,FARNESOL RECEPTOR H ...	Mutations
	--	--	HUMAN	--
	--	--	HUMAN	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402