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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN FOLATE RECEPTOR ALPHA IN COMPLEX WITH NOVEL ANTIFOLATE AGF183
DATE LAST MODIFIED
25 Dec 2019
RELEASE
10 Aug 2016
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
3.6
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.6B00594
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P15328 FOLR1, FOLR HOMO SAPIENS HUMAN
FR-ALPHA,ADULT FOLATE-BINDING PROTEIN,FBP,FOLATE R ...
Mutations
P15328 FOLR1, FOLR HOMO SAPIENS HUMAN
FR-ALPHA,ADULT FOLATE-BINDING PROTEIN,FBP,FOLATE R ...
Mutations
P15328 FOLR1, FOLR HOMO SAPIENS HUMAN
FR-ALPHA,ADULT FOLATE-BINDING PROTEIN,FBP,FOLATE R ...
Mutations
P15328 FOLR1, FOLR HOMO SAPIENS HUMAN
FR-ALPHA,ADULT FOLATE-BINDING PROTEIN,FBP,FOLATE R ...
Mutations
P15328 FOLR1, FOLR HOMO SAPIENS HUMAN
FR-ALPHA,ADULT FOLATE-BINDING PROTEIN,FBP,FOLATE R ...
Mutations
P15328 FOLR1, FOLR HOMO SAPIENS HUMAN
FR-ALPHA,ADULT FOLATE-BINDING PROTEIN,FBP,FOLATE R ...
Mutations
P15328 FOLR1, FOLR HOMO SAPIENS HUMAN
FR-ALPHA,ADULT FOLATE-BINDING PROTEIN,FBP,FOLATE R ...
Mutations
P15328 FOLR1, FOLR HOMO SAPIENS HUMAN
FR-ALPHA,ADULT FOLATE-BINDING PROTEIN,FBP,FOLATE R ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402