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3D Structure View

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GENERAL
TITLE
CRYSTAL STRUCTURE OF HSP90-ALPHA N-DOMAIN L107 MUTANT IN COMPLEX WITH 5-[4-(2-FLUORO-PHENYL)-5-OXO-4,5-DIHYDRO-1H-[1,2,4]TRIAZOL-3-YL]-N- FURAN-2-YLMETHYL-2,4-DIHYDROXY-N-METHYL-BENZAMIDE
DATE LAST MODIFIED
24 Jan 2018
RELEASE
6 Dec 2017
OBSOLETE
CLASSIFICATION
CHAPERONE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
1.64
RESOLUTION RANGE LOW
22.69
PUBMED ID
DOI
10.1038/S41467-017-02258-W
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P07900 HSP90AA1, HSP90A, HSPC1, HSPCA ESCHERICHIA COLI HUMAN
HEAT SHOCK 86 KDA,HSP86,LIPOPOLYSACCHARIDE-ASSOCIA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402