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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAINS OF METTL3/METTL14 COMPLEX WITH SAM
DATE LAST MODIFIED
8 Jan 2020
RELEASE
6 Jul 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
1.7
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.MOLCEL.2016.05.041
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q86U44 METTL3, MTA70 ESCHERICHIA COLI BL21(DE3) HUMAN MT-A70,METHYLTRANSFERASE-LIKE PROTEIN 3 HUMAN
MT-A70,METHYLTRANSFERASE-LIKE PROTEIN 3
Mutations
Q9HCE5 METTL14, KIAA1627 ESCHERICHIA COLI BL21(DE3) HUMAN METHYLTRANSFERASE-LIKE PROTEIN 14 HUMAN
METHYLTRANSFERASE-LIKE PROTEIN 14
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402