5KCV

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5KCV_A

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GENERAL

TITLE

CRYSTAL STRUCTURE OF ALLOSTERIC INHIBITOR, ARQ 092, IN COMPLEX WITH AUTOINHIBITED FORM OF AKT1

DATE LAST MODIFIED

27 Jul 2016

RELEASE

29 Jun 2016

OBSOLETE

CLASSIFICATION

TRANSFERASE/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.7

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.6B00619

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P31749	AKT1, PKB, RAC	SPODOPTERA FRUGIPERDA	HUMAN	PROTEIN KINASE B,PKB,PROTEIN KINASE B ALPHA,PKB AL ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402