5KDH

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5KDH_A

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GENERAL

TITLE

CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH A DIHYDROPYRIDOPYRIMIDINE SCAFFOLD INHIBITOR

DATE LAST MODIFIED

11 Dec 2019

RELEASE

2 Aug 2017

OBSOLETE

CLASSIFICATION

TRANSCRIPTION/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.5

RESOLUTION RANGE LOW

38.14

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.6B01336

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	O60885	BRD4, HUNK1	ESCHERICHIA COLI	HUMAN	PROTEIN HUNK1	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402